Mpox Virus: The Emerging Threat of a New Era

Mpox Virus: The Emerging Threat of a New Era

The Mpox virus, formerly known as the monkeypox virus, has become a resurgent concern in recent years, gaining more attention especially after the COVID-19 pandemic. Although first identified in humans in the 1970s, this virus was previously endemic to certain regions of Africa. However, in 2022, it spread globally and escalated into a significant public health crisis. In this article, we will explore what the Mpox virus is, how it spreads, its symptoms, and how we can protect ourselves.

What is the Mpox Virus?

The Mpox virus is part of the same family as the variola virus, which causes smallpox. Historically, smallpox caused devastating outbreaks, but widespread vaccination programs brought it under control. However, the Mpox virus is a less severe relative of smallpox and has a lower mortality rate .

Although named after monkeys, the virus is also found in other animals, particularly rodents. Human infection often results from direct contact with infected animals, though human-to-human transmission is also possible. The global spread of Mpox in recent years is linked to increased human travel and interactions.

Symptoms of Mpox Virus

Symptoms of Mpox infection generally appear within 5 to 21 days and resemble those of smallpox, though they are typically milder. Common symptoms include:

  • Fever: A high fever as the body responds to the viral infection.
  • Headaches and muscle aches: Intense pain in the head and muscles is common .
  • Swollen lymph nodes: A distinguishing feature from other viral infections, with swelling of lymph nodes .
  • Skin rashes: Rash typically starts on the face and then spreads to other parts of the body. These rashes can develop into blisters and lesions, which eventually scab over.

The symptoms usually last between 2 and 4 weeks. While the disease can be mild, individuals with weakened immune systems may experience more severe complications.

Transmission Pathways

The Mpox virus primarily spreads through contact with infected animals or humans. Transmission from animals to humans occurs through bites, scratches, or contact with body fluids. Human-to-human transmission can happen through prolonged face-to-face contact, direct contact with skin lesions, or respiratory droplets. Recent studies have shown that sexual contact may also play a role in the spread of the virus .

In the global outbreak of 2022, many cases were linked to close contact between men, although this does not imply that only one group is susceptible. Anyone can contract Mpox if exposed to the virus.

Treatment and Prevention

There is no specific treatment for Mpox, but vaccines and antiviral medications developed for smallpox have been shown to be effective against Mpox. For example, the smallpox vaccine provides up to 85% protection against Mpox .

To prevent the spread of the disease, experts recommend:

  • Avoiding contact with infected individuals or animals,
  • Avoiding materials contaminated with the virus,
  • Regularly washing hands,
  • Wearing protective gear like masks and gloves,
  • Vaccination of high-risk individuals.

Isolation of infected patients and contact tracing are also key strategies in managing outbreaks.

The Future of the Mpox Virus and Outbreak Management

The reemergence of the Mpox virus highlights the potential for new viruses and outbreaks to spread rapidly worldwide. Following the COVID-19 pandemic, it has become clear that public health systems must be better prepared for such events. Effective outbreak management, international cooperation, and robust vaccination strategies will be essential in preventing the further spread of the Mpox virus and other emerging threats .

While the Mpox virus may not pose the same level of threat as some other infectious diseases, its ability to disrupt communities and challenge health systems is not to be underestimated. As global interconnectivity increases, vigilance and continued research will be critical in safeguarding public health.


References:

  1. World Health Organization. “Monkeypox: Key Facts.” WHO, July 2022.
  2. Centers for Disease Control and Prevention (CDC). “Monkeypox: What You Need to Know.” CDC, June 2022.
  3. European Centre for Disease Prevention and Control. “Monkeypox Multi-Country Outbreak.” ECDC, August 2022.
  4. Thornhill JP, Barkati S, Walmsley S, et al. "Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022." The New England Journal of Medicine, 2022.
  5. Breman JG, Henderson DA. "Monkeypox: A Continuing Problem in the Face of Smallpox Eradication." Bulletin of the World Health Organization, 1976.
  6. Jezek Z, Grab B, Szczeniowski M, et al. "Human Monkeypox: Secondary Attack Rates." Bulletin of the World Health Organization, 1988.
  7. Reed KD, Melski JW, Graham MB, et al. "The Detection of Monkeypox in Humans in the Western Hemisphere." The New England Journal of Medicine, 2004.
  8. Sklenovská N, Van Ranst M. "Emergence of Monkeypox as the Most Important Orthopoxvirus Infection in Humans." Frontiers in Public Health, 2018.
  9. Adler H, Gould S, Hine P, et al. "Clinical Features and Management of Human Monkeypox: A Retrospective Observational Study in the UK." The Lancet Infectious Diseases, 2022.
  10. Fine PEM, Jezek Z, Grab B, Dixon H. "The Transmission Dynamics of Monkeypox in Human Populations." Philosophical Transactions of the Royal Society B, 1988.
  11. European Medicines Agency. “EMA Recommends Approval of Vaccine Imvanex for Monkeypox.” EMA, July 2022.